Title: Expected Prescription Error (EPE) Scores of Cancer Drugs in Egypt: A New Method of Data Extraction from a Questionnaire Based Study
Author(s): Mahmoud Abbass Ellithy.PhD.1, Doaa Atef Soliman. PhD.2, Omar Abdel-Rahman. PhD.3, L. Elwakil. PhD.4, N.S. El-Baghdady. MSc.5, Wesam Moustafa El Bakly. PhD.6, Wesam R. ELghamry PhD7
Affiliation: 1, 2,3,4,7Faculty of Medicine, Ain Shams University, Elabbassia square, Cairo. Egypt.
5Faculty of Pharmacy, Ain Shams University, Elabbassia square, Cairo, Egypt.
6Faculty of pharmacy, Modern University for Technology and Information, El-hadaba El-Wosta, Mokatam, 5th district, Cairo, Egypt.
7Faculty of Medicine Ain Shams University, Elabbassia square, Cairo, Egypt
Many pharmaceutical aspects are crucial for cancer drugs efficacy as proper dosing schedules, medical contraindications, proper methods and timing of administration, proper preparations and storage procedures, drug interactions and dose relation to meals in oral drugs. Medication related errors were a significant cause of morbidity and mortality. Medication errors were estimated to account for more than 7000 deaths annually.(1)
Leape and colleagues reported more than 15 types of medication errors: wrong dose, wrong choice, wrong drug, known allergy, missed dose, wrong time, wrong frequency, wrong technique, drug-drug interactions, wrong route, extra dose, failure to act on test, equipment failure, inadequate monitoring, preparation error and others. The majority of physician’s errors were wrong dose, wrong choice of drug and known allergy. (2)
Tissot and Vanden Bernt examined only administartion stage errors and reported very different rates. Tissot reported 6.6 percent of the 2009 observed doses were in error, most from wrong dose, wrong rate and wrong preparation technique. Excluding wrong time error, Van den Bernt reported a 33 percent error rate that included preparation errors with diluent solvent issues, infusion rates errors and chemical incompatibility of intravenous drugs.(3,4)